EMMA projects - Wellcome Trust Knockout Mouse Resource
The Wellcome Trust has negotiated and funded the acquisition of a limited number of gene knockout mouse strains and associated phenotypic data from Deltagen Inc. and Lexicon Pharmaceuticals. This resource will be archived and distributed through EMMA and provides researchers with unprecedented access to two private collections of knockout mice. These valuable models will not only aid the study of human disease but will also form part of a genome-wide library of knockout mice. Comprehensive information on such a large group of mouse strains has never been available to public sector researchers before and is expected to accelerate the discovery of functional genes effecting human health and disease. Under the terms of the world-wide academic licence granted to the Trust for the use of the mouse lines by Deltagen and Lexicon, researchers will be able to share the mouse lines acquired with other academic collaborators.
To assist the Wellcome Trust in tracking the outputs of the research to which it has contributed either wholly or in part, the Trust's contributions must be acknowledged in all publications according to the Trust's Guidance for Research Publication Acknowledgement Practice. EMMA customers must refer to the 'Wellcome Trust Knockout Mouse Resource'.
Two calls for proposals have already been made and 87 lines have been awarded. These lines are currently being rederived and archived and will be made available to the research community through EMMA.
DELTAGEN STRAINS on the list of available EMMA strains
LEXICON STRAINS on the list of available EMMA strains