EMMA partner
GSF - Institute of Experimental Genetics, Munich, Germany
Ingolstaedter Landstrasse 1
D-85764 Neuherberg
Germany
The GSF-National Research Center for Environment and Health - located in Neuherberg/Munich - is a member of the Helmholtz Association
of National Research.
The Institute of Experimental Genetics (IEG) is interested in the functional analysis of
mammalian genomes using the mouse as a model organism to carry out analyses of gene function and to elucidate the pathogenesis of
diseases. Within a large scale ENU mutagenesis screen numerous new mutant lines are produced, leading to the identification of new genes
and to valuable insight into gene function. In the newly established German Mouse Clinic (GMC) standardized and comprehensive
phenotypic analysis of mouse mutants from various sources are developed and offered.
To accomplish the increasing number of mutants the expertise in cryopreservation and archiving has been built up since 1997, resulting in
an archive of over 800 mutant mouse lines (sperm and embryos). Complemented with reproductive techniques, cryopreservation of
germplasm provides a secure and economical management of storing the enormous numbers of new mutations generated enabling their
use for future research.
Prof. Dr. Martin Hrabé de Angelis is head of the Institute of Experimental Genetics as well as the EMMA Director. Among his responsibilities in the overall coordination of the EMMA consortium is the supervision of the EMMA Project Office that is also located at the institute. Dr. Michael Hagn and Dr. Sabine Fessele are the EMMA project managers. Dr. Susan Marschall, responsible for the Cryo-Unit of the IEG, has worked in the field of cyropreservation for many years.
The GSF-IEG is a partner of the PRIME, EUMORPHIA and EUCOMM European Networks and of the National Genome Research Network of the German Federal Ministry of Education and Research (NGFN II).